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The constant innovations in healthcare generate new costs for the sector and, therefore, every new technology to be incorporated goes through the meticulous process of Healthcare Technology Assessments (HTA), which serve as a basis for decision-making. One

Healthcare Technology Assessments (HTA)are important tools for the (dis)incorporation of technologies and, for this purpose, they make use of various methods of clinical epidemiology and biostatistics to generate scientific evidence, making it possible to offer managers for

[:pb] Health economics assessments began to be used in the 1960s, with the aim of evaluating and comparing existing information on different technologies in order to make decisions about the best way to allocate resources. Since then,

[:pb]The cost-effectiveness analysis (ACE) is currently the most suitable economic evaluation methodology to compare two or more healthcare technologies in order to choose the one that will bring more benefits, preferably at the lowest cost. Used in

[:pb] One of the biggest sources of innovation in the pharmaceutical industry today is biological medicines. The high complexity that they have demands more specialization in all the processes of elaboration of this technology. In this context,